Antithrombin iii human

Antithrombin iii human is an unknown pharmaceutical. It is currently being investigated in clinical studies.

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Commercial

Therapeutic Areas

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EMA

Thrombate

Drug Products

FDA

EMA

Reference product - 351(a)

Interchangeable product - 351(k)

Biosimilar product - 351(k)

Antithrombin iii (human)

Tradename	Proper name	Company	Number	Date	Products
Thrombate Iii	Antithrombin III (Human)	Grifols	A-103196 RX	1991-12-30	1 products
Thrombate Iii	Antithrombin III (Human)	Grifols	N-103196 RX	1991-12-30	1 products

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EMA

Brand Name	Status	Last Update
thrombate iii	Biologic Licensing Application	2010-01-10

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Agency Specific

FDA

EMA

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ATC Codes

B: Blood and blood forming organ drugs

— B01: Antithrombotic agents

— B01A: Antithrombotic agents

— B01AB: Heparin group antithrombotic drugs

— B01AB02: Antithrombin iii

HCPCS

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Clinical

Clinical Trials

4645 clinical trials

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Indications Phases 4

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Breast neoplasms	D001943	EFO_0003869	C50	28	51	155	1	100	317
Neoplasms	D009369	—	C80	45	41	80	1	72	218
Lymphoma	D008223	—	C85.9	25	50	39	1	17	121
Pancreatic neoplasms	D010190	EFO_0003860	C25	18	26	27	1	17	78
Syndrome	D013577	—	—	7	13	21	1	27	65
Type 2 diabetes mellitus	D003924	EFO_0001360	E11	4	3	37	6	12	59
Hiv infections	D015658	EFO_0000764	B20	7	7	37	1	10	58
Heart failure	D006333	EFO_0003144	I50	5	5	8	4	36	56
Covid-19	D000086382	—	U07.1	5	9	32	1	16	56
Periodontitis	D010518	EFO_0000649	K05.3	2	4	3	4	45	54

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Indications Phases 3

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Non-small-cell lung carcinoma	D002289	—	—	27	92	109	—	39	240
Lung neoplasms	D008175	—	C34.90	19	55	51	—	50	157
Colorectal neoplasms	D015179	—	—	15	32	56	—	43	130
Melanoma	D008545	—	—	42	61	16	—	23	128
Prostatic neoplasms	D011471	—	C61	10	17	62	—	33	118
Ovarian neoplasms	D010051	EFO_0003893	C56	22	27	32	—	28	102
Carcinoma	D002277	—	C80.0	14	26	54	—	19	101
Multiple myeloma	D009101	—	C90.0	22	35	35	—	12	98
Leukemia	D007938	—	C95	14	25	42	—	13	89
Plasma cell neoplasms	D054219	—	—	20	29	24	—	12	80

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Indications Phases 2

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Malocclusion	D008310	—	M26.4	—	1	—	—	10	11
Anxiety	D001007	EFO_0005230	F41.1	1	1	—	—	9	10
Blast crisis	D001752	—	—	3	2	—	—	5	9
Salivary gland neoplasms	D012468	EFO_0003826	D11	2	4	—	—	3	8
Hairy cell leukemia	D007943	—	C91.4	3	1	—	—	4	8
Leukemia myeloid chronic atypical bcr-abl negative	D054438	—	C92.2	1	2	—	—	4	7
Neutrophilic leukemia chronic	D015467	—	D47.1	2	2	—	—	4	7
Residual neoplasm	D018365	—	—	1	3	—	—	4	7
Joint diseases	D007592	—	M12.9	1	2	—	—	4	6
Meningioma	D008579	EFO_0003098	D32.9	—	4	—	—	2	6

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Indications Phases 1

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Metabolic syndrome	D024821	EFO_0000195	E88.810	1	—	—	—	10	11
Pressure ulcer	D003668	—	L89	1	—	—	—	7	8
Cigarette smoking	D000073865	—	—	1	—	—	—	4	5
Metabolic diseases	D008659	EFO_0000589	E88.9	1	—	—	—	4	5
Biphenotypic leukemia acute	D015456	—	C95.0	1	—	—	—	2	3
Mast-cell leukemia	D007946	—	C94.3	1	—	—	—	2	3
Systolic heart failure	D054143	EFO_1001207	I50.20	1	—	—	—	2	3
Neurologic manifestations	D009461	—	—	1	—	—	—	1	2
Penile neoplasms	D010412	—	C60	1	—	—	—	1	2
Plasmablastic lymphoma	D000069293	—	C83.3	1	—	—	—	1	2

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Indications Without Phase

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Cerebral palsy	D002547	—	G80	—	—	—	—	16	16
Exercise	D015444	EFO_0000483	—	—	—	—	—	10	10
Motor activity	D009043	EFO_0003940	—	—	—	—	—	10	10
Neck pain	D019547	—	M54.2	—	—	—	—	9	9
Angle class iii malocclusion	D008313	—	M26.213	—	—	—	—	9	9
Malnutrition	D044342	EFO_0008572	E40-E46	—	—	—	—	7	7
Death	D003643	PATO_0001422	—	—	—	—	—	7	7
Aging	D000375	GO_0007568	R41.81	—	—	—	—	7	7
Prognathism	D011378	—	—	—	—	—	—	7	7
Paralysis	D010243	—	—	—	—	—	—	6	6

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Epidemiology

Epidemiological information for investigational and approved indications

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Drug

General

Drug common name	Antithrombin iii human
INN	antithrombin iii
Description	Antithrombin iii human is an unknown pharmaceutical. It is currently being investigated in clinical studies.
Classification	Unknown
Drug class	—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)	—